Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501660 | 0.95 | CCR4 (0.34) | CCR4TDP1ALDH1A1TP53HSP90AA1 | |
| SCHEMBL7824414 | 0.84 | ALDH1A1 (0.52) | CCR4TDP1ALDH1A1TP53HSP90AA1 | |
| SCHEMBL6299109 | 0.74 | ABL1 (0.46) | ALDH1A1CYP3A4SMN1; SMN2L3MBTL1CYP2D6 | |
| SCHEMBL2722703 | 0.74 | ALDH1A1 (0.60) | TDP1ALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL11347331 | 0.74 | S1PR1 (0.39) | CCR4TDP1ALDH1A1TP53HSP90AA1 | |
| SCHEMBL6135280 | 0.73 | ABL1 (0.53) | ALDH1A1SMN1; SMN2ADRA2A | |
| SCHEMBL11345753 | 0.71 | ALDH1A1 (0.42) | TDP1ALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL26644640 | 0.71 | ALDH1A1 (0.42) | TDP1ALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL20246488 | 0.70 | EPHX2 (0.52) | — | |
| SCHEMBL1453959 | 0.70 | ALDH1A1 (0.50) | TDP1ALDH1A1TP53HSP90AA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082414-A2 | CONCOMITANT DRUGS OF A SULFONAMIDE AND ANOTHER THERAPEUTIC AGENT | ASTELLAS PHARMA INC. (JP) | 2005-09-09 | — | — | WO | disclosed |
| EP-1136492-A1 | SULFONAMIDE COMPOUNDS AND USES THEREOF AS MEDICINES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-26 | — | — | EP | disclosed |