Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 9/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10911498 | 0.77 | — | — | |
| SCHEMBL7105035 | 0.77 | AHR (0.56) | AHRMAOAMAOBALOX5 | |
| SCHEMBL10431873 | 0.76 | PPIA (0.31) | — | |
| SCHEMBL9820998 | 0.76 | ATM (0.31) | — | |
| SCHEMBL17509821 | 0.70 | MAOA (0.41) | MAOAMAOBLMNASMN1; SMN2 | |
| SCHEMBL125113 | 0.69 | MAOA (0.56) | AHRMAOAMAOBALOX5LMNA | |
| SCHEMBL29724179 | 0.69 | MAOA (0.56) | AHRMAOAMAOBALOX5LMNA | |
| SCHEMBL3102452 | 0.69 | MAOA (0.56) | AHRMAOAMAOBALOX5LMNA | |
| SCHEMBL8668546 | 0.69 | MAOA (0.56) | AHRMAOAMAOBALOX5LMNA | |
| SCHEMBL29383458 | 0.69 | MAOA (0.56) | AHRMAOAMAOBALOX5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005077868-A2 | CONGENERIC, CHLORINATED, BROMINATED AND/OR IODISED, FLUORINATED AROMATIC COMPOUNDS COMPRISING TWO BENZOL RINGS IN THEIR BASIC STRUCTURE, METHOD FOR THEIR PRODUCTION AND USE THEREOF | CHIRON AS (NO) | 2005-08-25 | — | — | WO | disclosed |