SCHEMBL8668546

SCHEMBL8668546

c1ccc2c(c1)Oc1ccccc1Oc1ccccc1Oc1ccccc1Oc1ccccc1Oc1ccccc1O2

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.56
MAOB P27338 2/20 0.56
ALOX5 P09917 1/20 0.56
AHR P35869 5/20 0.55
ABCG2 Q9UNQ0 1/20 0.47
ITGB2 P05107 1/20 0.47
ICAM1 P05362 1/20 0.47
ITGAL P20701 1/20 0.47
TRPA1 O75762 1/20 0.43
KDM4E B2RXH2 1/20 0.43
MAPK1 P28482 1/20 0.43
ATM Q13315 1/20 0.43
GAA P10253 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
P2RX4 Q99571 1/20 0.40
LMNA P02545 1/20 0.40
CRHBP P24387 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29724179 1.00 MAOA (0.56) MAOAMAOBALOX5AHRABCG2
SCHEMBL4571011 1.00 MAOA (0.56) MAOAMAOBALOX5AHRABCG2
SCHEMBL15613 1.00
SCHEMBL125113 1.00 MAOA (0.56) MAOAMAOBALOX5AHRABCG2
SCHEMBL3102452 1.00 MAOA (0.56) MAOAMAOBALOX5AHRABCG2
SCHEMBL8671027 1.00 MAOA (0.56) MAOAMAOBALOX5AHRABCG2
SCHEMBL29383458 1.00 MAOA (0.56) MAOAMAOBALOX5AHRABCG2
Water SCHEMBL1286428 0.96 MAOA (0.53) MAOAMAOBALOX5AHRABCG2
Hydrochloric Acid SCHEMBL7263461 0.96 MAOA (0.53) MAOAMAOBALOX5AHRABCG2
Hydrochloric Acid SCHEMBL5958364 0.96 MAOA (0.53) MAOAMAOBALOX5AHRABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5716551-A ULTRAVIOLET RADIATION CURABLE THERMOSETTING MIXTURE CONTAINING ELECTROCONDUCTIVE ALKALI-DOPED CROWN COMPOUNDS; QUICK-CURING TECH SPRAY, INC. (US) 1998-02-10 US disclosed