Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.55 |
| ▸ | MMP13 | P45452 | 2/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011648 | 0.84 | SLC6A4 (0.42) | MMP13ADAM17MMP1 | |
| Hydrochloric Acid SCHEMBL6011657 | 0.83 | SLC6A4 (0.41) | MMP13ADAM17MMP1 | |
| SCHEMBL7602931 | 0.83 | GPR119 (0.66) | GPR119MMP13 | |
| SCHEMBL6011358 | 0.82 | GPR119 (0.43) | GPR119MMP13ADAM17MMP1 | |
| SCHEMBL6011574 | 0.78 | GPR119 (0.58) | GPR119 | |
| SCHEMBL6011356 | 0.78 | GPR119 (0.71) | GPR119 | |
| SCHEMBL28978030 | 0.78 | GPR119 (0.58) | GPR119MMP13 | |
| SCHEMBL6011384 | 0.77 | GPR119 (0.57) | GPR119 | |
| SCHEMBL7607099 | 0.77 | GPR119 (0.57) | GPR119MMP13 | |
| SCHEMBL8444728 | 0.77 | KDM4E (0.58) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572650-A1 | NOVEL PIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR CCR5 | AstraZeneca AB (SE) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056773-A1 | NOVEL PIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR CCR5 | ASTRAZENECA AB (SE) | 2004-07-08 | — | — | WO | disclosed |