Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 6/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6011657 | 0.99 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3HTR3AKCNH2 | |
| SCHEMBL6466874 | 0.84 | GPR119 (0.55) | ADAM17MMP13MMP1 | |
| SCHEMBL6011410 | 0.84 | CHRM1 (0.43) | SLC6A4SLC6A2SLC6A3HTR3AKCNH2 | |
| SCHEMBL7604882 | 0.83 | CA12 (0.45) | SLC6A4CHRM1CHRM3TDP1ITGB3 | |
| SCHEMBL6011358 | 0.80 | GPR119 (0.43) | ADAM17MMP13MMP2MMP9MMP8 | |
| SCHEMBL6011457 | 0.80 | ALDH1A1 (0.51) | SLC6A4ITGB3ITGA2BITGAVCHRM2 | |
| SCHEMBL6011960 | 0.80 | KMT2A (0.60) | SLC6A4ADAM17MMP13MMP2MMP9 | |
| SCHEMBL6469248 | 0.77 | CHRM1 (0.45) | SLC6A4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL8555011 | 0.76 | ALDH1A1 (0.51) | CHRM1CHRM3ALDH1A1 | |
| SCHEMBL6011463 | 0.76 | CHRM1 (0.44) | MMP2MMP9MMP8CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189650-A1 | Novel piperidine derivatives as modulators of chemokine receptor ccr5 | ASTRAZENECA AB (SE) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189650-A1 | Novel piperidine derivatives as modulators of chemokine receptor ccr5 | CCR5, CCR2, CCR1 | SLC6A4 2570/4885SLC6A2 2953/4885SLC6A3 1787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.