Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | LIPC | P11150 | 2/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043175 | 0.90 | DAGLA (0.46) | CTSSFAAHCES1DAGLAALDH1A1 | |
| SCHEMBL6462778 | 0.89 | KDM4E (0.39) | CTSSFAAHCES1DAGLAALDH1A1 | |
| SCHEMBL6467366 | 0.87 | DAGLA (0.47) | FAAHCES1DAGLAALDH1A1KMT2A | |
| SCHEMBL6463188 | 0.87 | DAGLA (0.48) | FAAHCES1DAGLAALDH1A1KMT2A | |
| SCHEMBL5731270 | 0.86 | TACR2 (0.43) | CTSSFAAHCES1DAGLAALDH1A1 | |
| SCHEMBL6467383 | 0.83 | FAAH (0.40) | CTSSFAAHCES1DAGLAALDH1A1 | |
| SCHEMBL6467703 | 0.83 | FAAH (0.40) | FAAHCES1DAGLAALDH1A1KMT2A | |
| SCHEMBL6062448 | 0.83 | FAAH (0.38) | CTSSFAAHCES1DAGLAALDH1A1 | |
| SCHEMBL6461887 | 0.82 | DRD2 (0.41) | FAAHCES1DAGLAALDH1A1KMT2A | |
| SCHEMBL6463801 | 0.81 | FAAH (0.38) | CTSSFAAHCES1DAGLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | claimed |
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | claimed |