SCHEMBL6467568

SCHEMBL6467568

Cc1ccc(S(=O)(=O)NC(=O)NCc2cccc(CNC(=O)NS(=O)(=O)c3ccc(C)cc3)c2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 5/20 0.78
ALDH1A1 P00352 2/20 0.69
MAPT P10636 1/20 0.69
SMN1; SMN2 Q16637 1/20 0.66
CYP19A1 P11511 1/20 0.64
CYP2C9 P11712 2/20 0.58
LMNA P02545 2/20 0.58
NPSR1 Q6W5P4 1/20 0.58
ALB P02768 1/20 0.58
TSHR P16473 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
KMT2A Q03164 1/20 0.56
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA9 Q16790 1/20 0.55
GAA P10253 1/20 0.55
EGFR P00533 1/20 0.55
ERBB2 P04626 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23447448 0.94 FBP1 (0.78) FBP1ALDH1A1MAPTSMN1; SMN2CYP19A1
SCHEMBL5186630 0.90 ALDH1A1 (0.75) FBP1ALDH1A1MAPTSMN1; SMN2CYP2C9
SCHEMBL6466794 0.88 ALDH1A1 (0.86) FBP1ALDH1A1MAPTSMN1; SMN2CYP2C9
SCHEMBL23447460 0.88 FBP1 (0.61) FBP1ALDH1A1MAPTSMN1; SMN2CYP19A1
SCHEMBL2006119 0.87 FBP1 (1.00) FBP1ALDH1A1MAPTSMN1; SMN2
SCHEMBL8415594 0.86 CA12 (0.70) FBP1ALDH1A1MAPTCYP2C9LMNA
SCHEMBL6467702 0.85 CYP19A1 (0.67) FBP1ALDH1A1MAPTSMN1; SMN2CYP19A1
SCHEMBL2007031 0.80 FBP1 (1.00) FBP1ALDH1A1MAPTSMN1; SMN2
SCHEMBL5931104 0.80 ALDH1A1 (0.79) FBP1ALDH1A1MAPTSMN1; SMN2CYP2C9
SCHEMBL8291630 0.79 ALDH1A1 (0.70) FBP1ALDH1A1MAPTSMN1; SMN2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542556-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP claimed
EP-0535887-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP claimed
US-5314859-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-05-24 US claimed
US-5256618-A Using a sulfonylurea or -thiourea-type developer and leuco dye. resistance to oil and fats, e.g, plasticizer, moisture and heat; colorfastness; storage stability; thermography OJI PAPER CO., LTD. (JP) 1993-10-26 US claimed
EP-0542556-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-05-19 EP claimed
EP-0535887-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-04-07 EP claimed
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-0615859-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-06-03 EP disclosed
EP-0792754-A2 Heat sensitive recording material Oji Paper Co., Ltd. (JP) 1997-09-03 EP disclosed
US-5449657-A Sulfonyl (thio)ureas NEW OJI PAPER CO., LTD. (JP) 1995-09-12 US disclosed
EP-0542556-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP disclosed
EP-0535887-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP disclosed
EP-0615859-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-09-21 EP disclosed
US-5314859-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-05-24 US disclosed
US-5256618-A Using a sulfonylurea or -thiourea-type developer and leuco dye. resistance to oil and fats, e.g, plasticizer, moisture and heat; colorfastness; storage stability; thermography OJI PAPER CO., LTD. (JP) 1993-10-26 US disclosed
EP-0542556-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-05-19 EP disclosed
EP-0535887-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-04-07 EP disclosed