Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2711071 | 0.93 | KMT2A (0.36) | KMT2AKDM4EL3MBTL1TSHRALDH1A1 | |
| SCHEMBL2712407 | 0.84 | KMT2A (0.37) | KMT2AKDM4EL3MBTL1TSHRALDH1A1 | |
| SCHEMBL3510503 | 0.84 | ALOX15 (0.44) | KMT2AKDM4EL3MBTL1TSHRALDH1A1 | |
| SCHEMBL2711076 | 0.81 | KMT2A (0.35) | KMT2AKDM4EL3MBTL1TSHRALDH1A1 | |
| SCHEMBL21144538 | 0.78 | TSHR (0.61) | KDM4EL3MBTL1TSHRALDH1A1LMNA | |
| SCHEMBL2021183 | 0.77 | TTR (0.38) | KMT2AKDM4ETSHRALDH1A1MEN1 | |
| SCHEMBL2018841 | 0.76 | KDM4E (0.42) | KMT2AKDM4EL3MBTL1TSHRALDH1A1 | |
| SCHEMBL11956572 | 0.75 | TSHR (0.69) | KDM4EL3MBTL1TSHRALDH1A1LMNA | |
| SCHEMBL165562 | 0.74 | KDM4E (0.51) | KMT2AKDM4EL3MBTL1TSHRALDH1A1 | |
| SCHEMBL2719086 | 0.72 | ALOX15 (0.48) | KMT2AKDM4EL3MBTL1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |