Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SDHB | P21912 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 5/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2711071 | 0.85 | KMT2A (0.36) | KMT2AKDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL2712407 | 0.82 | KMT2A (0.37) | KMT2AKDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL6468199 | 0.81 | KMT2A (0.40) | KMT2AKDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL2709690 | 0.76 | ALDH1A1 (0.55) | KMT2AKDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL2018841 | 0.72 | KDM4E (0.42) | KMT2AKDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL3855487 | 0.68 | KDM4E (0.39) | KMT2AKDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL2727661 | 0.68 | GLRA3 (0.43) | KMT2AKDM4EALDH1A1MEN1HSD17B10 | |
| SCHEMBL3863182 | 0.67 | BACE1 (0.41) | KMT2AKDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL3510503 | 0.66 | ALOX15 (0.44) | KMT2AKDM4EALDH1A1L3MBTL1MEN1 | |
| SCHEMBL3854398 | 0.65 | BACE1 (0.38) | KMT2AKDM4EALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |