⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10532368 | 0.92 | LOXL2 (0.55) | — | |
| SCHEMBL10238963 | 0.83 | LOXL2 (0.59) | — | |
| SCHEMBL12893452 | 0.79 | LOXL2 (0.55) | — | |
| SCHEMBL22241346 | 0.78 | LOXL2 (0.44) | — | |
| SCHEMBL1211655 | 0.78 | LOXL2 (0.53) | — | |
| SCHEMBL1348600 | 0.77 | — | — | |
| SCHEMBL2642497 | 0.77 | — | — | |
| SCHEMBL116309 | 0.77 | — | — | |
| SCHEMBL7413054 | 0.77 | — | — | |
| SCHEMBL29893902 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084724-A | Method for preparing aryl nitrile by copper-catalyzed oxidation and cleavage of alkyl-substituted aromatic ring and aromatic heterocyclic carbon-carbon bond | 中国科学院大连化学物理研究所 | 2024-05-28 | — | — | CN | disclosed |
| US-20230295131-A1 | INHIBITORS OF RHO-ASSOCIATED COILED-COIL KINASE | ANGION BIOMEDICA CORP. | 2023-09-21 | — | — | US | disclosed |
| US-11737463-B2 | Pyridine and pyrazine compounds | BASF SE (DE) | 2023-08-29 | — | — | US | disclosed |
| US-20230257362-A1 | TRIAZOLONE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2023-08-17 | — | — | US | disclosed |
| EP-4223739-A1 | 3,6-BIS(CYANOMETHYLIDENE)CYCLOHEXA-1,4-DIENE COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONIC DEVICES | Novaled GmbH (DE) | 2023-08-09 | — | — | EP | disclosed |
| US-20230203010-A1 | BICYCLIC AMINE CDK12 INHIBITORS | INCYTE CORPORATION | 2023-06-29 | — | — | US | disclosed |
| US-20230142119-A1 | TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-05-11 | — | — | US | disclosed |
| US-11584738-B2 | LPA receptor antagonists and uses thereof | GILEAD SCIENCES, INC. (US) | 2023-02-21 | — | — | US | disclosed |
| US-11566001-B2 | Hepatitis B capsid assembly modulators | VenatoRx Pharmaceuticals, Inc. (US) | 2023-01-31 | — | — | US | disclosed |
| US-20230025510-A1 | BIARYL ETHER-TYPE QUINAZOLINE DERIVATIVES | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-01-26 | — | — | US | disclosed |
| US-20080293718-A1 | Novel 2-Amino-Imidazole-4-One Compounds and Their Use in the Manufacture of a Medicament to Be Used in the Treatment of Cognitive Impairment, Alzheimer's Disease, Neurodegeneration and Dementia | ASTRAZENECA AB (SE) | 2008-11-27 | — | — | US | disclosed |
| US-20070129367-A1 | Pyridine derivatives as cb2 receptor modulators | GLAXO GROUP LIMITED (GB) | 2007-06-07 | — | — | US | disclosed |
| US-20070129367-A1 | Pyridine derivatives as cb2 receptor modulators | GLAXO GROUP LIMITED (GB) | 2007-06-07 | — | — | US | disclosed |
| EP-0799207-B1 | PROCESS FOR THE PREPARATION OF FLUORINATED HETEROCYCLIC COMPOUNDS | F2 CHEMICALS LIMITED (GB) | 1999-06-09 | — | — | EP | disclosed |
| US-5859255-A | Process for the preparation of fluorinated heterocyclic compounds | F2 CHEMICALS LTD. (GB) | 1999-01-12 | — | — | US | disclosed |
| CN-1170406-A | Preparation of fluorinated heterocyclic compounds | F2 CHEMICAL PRODUCTS LTD (GB) | 1998-01-14 | — | — | CN | disclosed |
| EP-0799207-A1 | PROCESS FOR THE PREPARATION OF FLUORINATED HETEROCYCLIC COMPOUNDS | BNFL FLUOROCHEMICALS LTD. (GB) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019456-A1 | PROCESS FOR THE PREPARATION OF FLUORINATED HETEROCYCLIC COMPOUNDS | BNFL FLUOROCHEMICALS LTD. (GB) | 1996-06-27 | — | — | WO | disclosed |
| WO-1996003379-A1 | THE ALKOXYLATION OF HETEROCYCLIC COMPOUNDS IN THE PRESENCE OF FLUORINE | BNFL FLUOROCHEMICALS LTD. (GB) | 1996-02-08 | — | — | WO | disclosed |
| US-4786733-A | CONTACTING WITH FLUORINE GAS | ALLIED-SIGNAL INC. (US) | 1988-11-22 | — | — | US | disclosed |