SCHEMBL116309

SCHEMBL116309

OCc1ccnc(F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1211358 0.83 LOXL2 (0.59)
SCHEMBL1211287 0.79 LOXL2 (0.55)
SCHEMBL16675785 0.79 PRKCI (0.64)
SCHEMBL7413054 0.77
SCHEMBL2642497 0.77
SCHEMBL6468413 0.77
SCHEMBL1348600 0.77
SCHEMBL3994643 0.77
SCHEMBL29893902 0.77
SCHEMBL501592 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119056265-A Reverse osmosis membrane, high-recovery reverse osmosis device containing reverse osmosis membrane and application of reverse osmosis membrane 杭州上拓环境科技股份有限公司 2024-12-03 CN claimed
CN-117089054-A Method for preparing polyurethane modified alkyd resin and preparation of high-gloss wear-resistant varnish 扬州市祥华新材料科技有限公司 2023-11-21 CN claimed
CN-116478413-A Method for modifying alkyd resin by acrylic acid prepolymer block type and application thereof 扬州市祥华新材料科技有限公司 2023-07-25 CN claimed
CN-116444776-A Method for preparing polyurethane modified alkyd resin and preparation of high-gloss wear-resistant varnish 扬州市祥华新材料科技有限公司 2023-07-18 CN claimed
CN-102712589-B Aryl-pyridine derivatives as aldosterone synthase inhibitors NOVARTIS AG 2015-05-13 CN claimed
US-20260028365-A1 TYROSINE KINASE 2 INHIBITORS AND USES THEREOF BIOGEN MA INC (US) 2026-01-29 US disclosed
EP-4577536-A1 PYRAZOLYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY Hotspot Therapeutics, Inc. (US) 2025-07-02 EP disclosed
US-20250171434-A1 SEC61 INHIBITORS AND USE THEREOF ENODIA THERAPEUTICS SAS (FR) 2025-05-29 US disclosed
EP-3936192-B1 PYRROLOPYRAZOLE DERIVATIVE DAIICHI SANKYO CO LTD (JP) 2025-04-09 EP disclosed
CN-117229205-B Preparation method and pharmaceutical application of phenyl acrylamide RHbDD1 inhibitor 中国医学科学院基础医学研究所 2025-03-21 CN disclosed
US-12240855-B2 Pyrrolopyrazole derivative DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-03-04 US disclosed
EP-4486451-A1 SEC61 INHIBITORS AND USE THEREOF Kezar Life Sciences, Inc. (US) 2025-01-08 EP disclosed
EP-1194425-B1 SUBSTITUTED BENZIMIDAZOLE AVENTIS PHARMA GMBH (DE) 2005-08-10 EP disclosed
WO-2004083235-A2 TIE-2 MODULATORS AND METHODS OF USE EXELIXIS INC. (US) 2004-09-30 WO disclosed
EP-1194425-A1 SUBSTITUTED BENZIMIDAZOLE Aventis Pharma Deutschland GmbH (DE) 2002-04-10 EP disclosed
US-6358978-B1 FOR THERAPY AND PROPHYLAXIS OF RHEUMATOID ARTHRITIS (IN THE CASE OF INFLAMMATION), OSTEOARTHRITIS, ASTHMA, CARDIAC INFARCT, ALZHEIMER'S DISEASE, OR ATHEROSCLEROSIS AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2002-03-19 US disclosed
US-6214847-B1 TREATMENT OF COGNITIVE OR NEUROLOGICAL DYSFUNCTION DUPONT PHARMACEUTICALS COMPANY 2001-04-10 US disclosed
WO-2001000610-A1 SUBSTITUTED BENZIMIDAZOLE AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2001-01-04 WO disclosed
EP-1003722-A1 CRYSTALLINE 10,10-BIS((2-FLUORO-4-PYRIDINYL)METHYL)-9(10H)-ANTHRACENONE AND AN IMPROVED PROCESS FOR PREPARING THE SAME Du Pont Pharmaceuticals Company (US) 2000-05-31 EP disclosed
WO-1999009010-A1 CRYSTALLINE 10,10-BIS((2-FLUORO-4-PYRIDINYL)METHYL)-9(10H)-ANTHRACENONE AND AN IMPROVED PROCESS FOR PREPARING THE SAME DU PONT PHARMACEUTICALS COMPANY (US) 1999-02-25 WO disclosed