Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | KIF5B | P33176 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468631 | 0.89 | QPCT (0.36) | MEN1KMT2AHSD17B10KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6465626 | 0.86 | CSF1R (0.39) | MEN1KMT2AKDM4EALDH1A1GAA | |
| Trifluoroacetic Acid SCHEMBL6469711 | 0.86 | RET (0.39) | MEN1KMT2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL6470340 | 0.85 | BRAF (0.41) | MEN1KMT2AHSD17B10KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6467968 | 0.83 | KDR (0.41) | MEN1KMT2AKDM4EALDH1A1HTT | |
| Trifluoroacetic Acid SCHEMBL6468628 | 0.83 | ADORA2B (0.34) | MEN1KMT2AHSD17B10KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6467438 | 0.83 | FGFR2 (0.41) | MEN1KMT2AKDM4EALDH1A1GAA | |
| Trifluoroacetic Acid SCHEMBL6466263 | 0.82 | MAPT (0.40) | MEN1KMT2AKDM4EALDH1A1RET | |
| Trifluoroacetic Acid SCHEMBL6467465 | 0.82 | MAPT (0.39) | MEN1KMT2AHSD17B10KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6469301 | 0.81 | KDR (0.37) | MEN1KMT2AKDM4EALDH1A1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124562-A1 | Bis-quinazoline compounds for the treatment of bacterial infections | REPLIDYNE, INC. | 2005-06-09 | — | — | US | claimed |
| WO-2005030131-A2 | BIS-QUINAZOLINE COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | REPLIDYNE, INC (US) | 2005-04-07 | — | — | WO | claimed |
| US-20050124562-A1 | Bis-quinazoline compounds for the treatment of bacterial infections | REPLIDYNE, INC. | 2005-06-09 | — | — | US | disclosed |
| WO-2005030131-A2 | BIS-QUINAZOLINE COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | REPLIDYNE, INC (US) | 2005-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124562-A1 | Bis-quinazoline compounds for the treatment of bacterial infections | POLI, POLK, POLB | MEN1 4218/4885KMT2A 2156/4885HSD17B10 2865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.