Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6135112 | 0.87 | PPARG (0.45) | PPARGPTGS2PTGS1MAPTALDH1A1 | |
| SCHEMBL6500342 | 0.86 | PPARG (0.48) | PPARGPTGS2PTGS1MAPTALDH1A1 | |
| SCHEMBL6134381 | 0.86 | MAPT (0.45) | PPARGPTGS2PTGS1MAPTALDH1A1 | |
| SCHEMBL6502741 | 0.86 | PPARG (0.42) | PPARGPTGS2PTGS1MAPTALDH1A1 | |
| SCHEMBL6501073 | 0.85 | PTGS2 (0.42) | PPARGPTGS2PTGS1MAPTALDH1A1 | |
| SCHEMBL6493091 | 0.85 | PTGS2 (0.43) | PPARGPTGS2PTGS1MAPTALDH1A1 | |
| SCHEMBL6299780 | 0.84 | MAPT (0.48) | PPARGPTGS2PTGS1MAPTALDH1A1 | |
| SCHEMBL6491984 | 0.84 | PTGS2 (0.38) | PPARGPTGS2PTGS1MAPTALDH1A1 | |
| SCHEMBL6491376 | 0.84 | ALDH1A1 (0.46) | PPARGPTGS2PTGS1MAPTALDH1A1 | |
| SCHEMBL6491654 | 0.83 | PPARG (0.45) | PPARGPTGS2PTGS1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082414-A2 | CONCOMITANT DRUGS OF A SULFONAMIDE AND ANOTHER THERAPEUTIC AGENT | ASTELLAS PHARMA INC. (JP) | 2005-09-09 | — | — | WO | disclosed |