Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1111908 | 0.84 | FBP1 (0.42) | FBP1HPGDMAPTNPC1RAB9A | |
| SCHEMBL10365892 | 0.81 | — | — | |
| Ammonia Solution, Strong SCHEMBL7247507 | 0.80 | FBP1 (0.48) | FBP1HPGDMAPTNPC1RAB9A | |
| SCHEMBL425181 | 0.78 | FBP1 (0.46) | FBP1HPGDMAPTNPC1RAB9A | |
| SCHEMBL9724074 | 0.77 | FBP1 (0.45) | FBP1HPGDMAPTNPC1RAB9A | |
| SCHEMBL17372958 | 0.75 | FBP1 (0.43) | FBP1HPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5315566 | 0.75 | FBP1 (0.43) | FBP1HPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL20669518 | 0.75 | FBP1 (0.43) | FBP1HPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL27916875 | 0.75 | FBP1 (0.43) | FBP1HPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28390983 | 0.75 | FBP1 (0.43) | FBP1HPGDMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |