SCHEMBL425181

SCHEMBL425181

CCCCSc1cccs1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.46
HPGD P15428 4/20 0.42
MAPT P10636 4/20 0.42
ALDH1A1 P00352 3/20 0.42
GAA P10253 2/20 0.42
HTT P42858 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
STAT6 P42226 1/20 0.42
KMT2A Q03164 1/20 0.42
HIF1A Q16665 1/20 0.42
PTGS2 P35354 4/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
S100A4 P26447 1/20 0.37
SOAT1 P35610 1/20 0.37
LMNA P02545 1/20 0.36
HDAC3 O15379 1/20 0.36
MAOA P21397 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9724074 0.94 FBP1 (0.45) FBP1HPGDMAPTALDH1A1GAA
SCHEMBL17372958 0.92 FBP1 (0.43) FBP1HPGDMAPTALDH1A1GAA
SCHEMBL27916875 0.92 FBP1 (0.43) FBP1HPGDMAPTALDH1A1GAA
SCHEMBL20669518 0.92 FBP1 (0.43) FBP1HPGDMAPTALDH1A1GAA
SCHEMBL5315566 0.92 FBP1 (0.43) FBP1HPGDMAPTALDH1A1GAA
SCHEMBL28390983 0.92 FBP1 (0.43) FBP1HPGDMAPTALDH1A1GAA
SCHEMBL10365892 0.88
Ammonia Solution, Strong SCHEMBL7247507 0.86 FBP1 (0.48) FBP1HPGDMAPTALDH1A1GAA
SCHEMBL28607626 0.80 FBP1 (0.46) FBP1HPGDMAPTALDH1A1HTT
SCHEMBL6369341 0.80 FBP1 (0.46) FBP1HPGDMAPTALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109817979-B Thiophene-1, 1-dioxane polymer as lithium battery positive electrode active material, and preparation method and application thereof 华北水利水电大学 2021-06-29 CN disclosed
US-10000450-B2 N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2018-06-19 US disclosed
US-10000450-B2 N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2018-06-19 US disclosed
CN-108165140-A Electroactive coating and composition for forming the same 博九通科技股份有限公司 2018-06-15 CN disclosed
CN-105295008-B Electroactive polymer solution or coating, composition and method for forming same, capacitor and method for making same, and antistatic article 博九通科技股份有限公司 2018-02-27 CN disclosed
US-20170166524-A1 N,N-SUBSTITUTED 3-AMINOPYRROLIDINE COMPOUNDS USEFUL AS MONOAMINES REUPTAKE INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2017-06-15 US disclosed
US-20170166524-A1 N,N-SUBSTITUTED 3-AMINOPYRROLIDINE COMPOUNDS USEFUL AS MONOAMINES REUPTAKE INHIBITORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2017-06-15 US disclosed
EP-3157976-A1 COMPOSITION AND METHOD FOR FORMING ELECTROACTIVE POLYMER SOLUTION OR COATING COMPRISING CONJUGATED HETEROAROMATIC POLYMER, ELECTROACTIVE POLYMER SOLUTION, CAPACITOR AND ANTISTATIC OBJECT COMPRISING THE ELECTROACTIVE COATING, AND SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR FABRICATING THE SAME Polym Technology Corporation (CN) 2017-04-26 EP disclosed
US-9611214-B2 N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2017-04-04 US disclosed
US-9611214-B2 N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2017-04-04 US disclosed
EP-1424942-B1 PORPHYRINS WITH ENHANCED MULTI-PHOTON ABSORPTION CROSS-SECTIONS FOR PHOTODYNAMIC THERAPY UNIV MONTANA STATE (US) 2008-12-31 EP disclosed
EP-1424942-A4 PORPHYRINS WITH ENHANCED MULTI-PHOTON ABSORPTION CROSS-SECTIONS FOR PHOTODYNAMIC THERAPY UNIV MONTANA STATE (US) 2005-11-23 EP disclosed
US-6953570-B2 Porphyrins with enhanced multi-photon absorption cross-sections for photodynamic therapy MONTANA STATE UNIVERSITY (US) 2005-10-11 US disclosed
EP-1424942-A1 PORPHYRINS WITH ENHANCED MULTI-PHOTON ABSORPTION CROSS-SECTIONS FOR PHOTODYNAMIC THERAPY Montana State University-Bozeman (US) 2004-06-09 EP disclosed
US-20030105070-A1 Porphyrins with enhanced multi-photon absorption cross-sections for photodynamic therapy NICKEL JOINT TRUST, THE 2003-06-05 US disclosed
WO-2003017846-A1 PORPHYRINS WITH ENHANCED MULTI-PHOTON ABSORPTION CROSS-SECTIONS FOR PHOTODYNAMIC THERAPY MONTANA STATE UNIVERSITY-BOZEMAN (US) 2003-03-06 WO disclosed
EP-0664825-B1 THIO-ESTER COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS SECR DEFENCE BRIT (GB) 1999-03-31 EP disclosed
US-5578242-A LIQUID CRYSTALS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND OF DEFENCE RESEARCH AGENCY (GB) 1996-11-26 US disclosed
EP-0664825-A1 THIO-ESTER COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND (GB) 1995-08-02 EP disclosed
WO-1994009085-A1 THIO-ESTER COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND OF THE DEFENCE RESEARCH AGENCY (GB) 1994-04-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030105070-A1 Porphyrins with enhanced multi-photon absorption cross-sections for photodynamic therapy HMBS, PPOX, PAICS FBP1 3875/4885HPGD 1382/4885MAPT 1431/4885
US-10000450-B2 N,N-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors SLC6A2, TPH1, SLC6A3 FBP1 2660/4885HPGD 1739/4885MAPT 1263/4885
US-20170166524-A1 N,N-SUBSTITUTED 3-AMINOPYRROLIDINE COMPOUNDS USEFUL AS MONOAMINES REUPTAKE INHIBITORS SLC6A2, TPH1, SLC6A3 FBP1 2660/4885HPGD 1739/4885MAPT 1263/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.