Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 5/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011372 | 0.86 | CHRM1 (0.44) | CHRM1CHRM3KMT2ANMT1CNR2 | |
| SCHEMBL6011463 | 0.86 | CHRM1 (0.44) | CHRM1CHRM3KMT2ANMT1CNR2 | |
| SCHEMBL6469254 | 0.86 | CHRM1 (0.44) | CHRM1CHRM3KMT2ANMT1CNR2 | |
| SCHEMBL8555011 | 0.86 | ALDH1A1 (0.51) | CHRM1CHRM3KMT2ANMT1CNR2 | |
| SCHEMBL6011594 | 0.86 | CRBN (0.46) | CHRM1CHRM3KMT2ANMT1CNR2 | |
| Hydrochloric Acid SCHEMBL5763987 | 0.84 | CRBN (0.45) | CHRM1CHRM3KMT2ANMT1CNR2 | |
| Hydrochloric Acid SCHEMBL6011621 | 0.84 | CHRM1 (0.43) | CHRM1CHRM3KMT2ANMT1CNR2 | |
| SCHEMBL6011410 | 0.83 | CHRM1 (0.43) | CHRM1CHRM3KMT2ACA2ALDH1A1 | |
| SCHEMBL6011550 | 0.81 | CA2 (0.42) | CHRM1CHRM3KMT2ACA2ALDH1A1 | |
| SCHEMBL6011640 | 0.81 | NMT1 (0.42) | CHRM1CHRM3KMT2ANMT1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572650-A1 | NOVEL PIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR CCR5 | AstraZeneca AB (SE) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056773-A1 | NOVEL PIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR CCR5 | ASTRAZENECA AB (SE) | 2004-07-08 | — | — | WO | disclosed |