Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | CA1 | P00915 | 6/20 | 0.48 |
| ▸ | CA9 | Q16790 | 6/20 | 0.48 |
| ▸ | CA12 | O43570 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563639 | 0.86 | TDP1 (0.57) | CA2CA1CA9CA12KMT2A | |
| SCHEMBL4691688 | 0.80 | GPR35 (0.53) | CA2CA1CA9CA12MAPK1 | |
| SCHEMBL4693020 | 0.78 | TDP1 (0.50) | MAPK1KMT2AMEN1TDP1L3MBTL1 | |
| SCHEMBL11854765 | 0.78 | MAPK1 (0.60) | MAPK1KMT2AMEN1TDP1L3MBTL1 | |
| Acetic Acid SCHEMBL29097243 | 0.78 | KMT2A (0.58) | CA2CA1CA9KMT2AMEN1 | |
| SCHEMBL27517614 | 0.78 | CA1 (0.47) | CA2CA1CA9CA12MAPK1 | |
| SCHEMBL4818765 | 0.78 | CA1 (0.51) | CA2CA1CA9CA12MAPK1 | |
| SCHEMBL370668 | 0.77 | KMT2A (0.70) | CA2CA1CA9CA12KMT2A | |
| SCHEMBL4158554 | 0.77 | KMT2A (0.70) | CA2CA1CA9CA12KMT2A | |
| SCHEMBL22719534 | 0.76 | KMT2A (0.68) | CA2CA1CA9CA12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |