Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.30 |
| ▸ | TUBB | P07437 | 1/20 | 0.30 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.30 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.30 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.30 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.30 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.30 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.30 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.30 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.30 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.30 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.30 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.30 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.30 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1480157 | 0.89 | DHODH (0.39) | DHODHNPC1RAB9AHSP90AA1HSP90AB1 | |
| SCHEMBL1480155 | 0.89 | DHODH (0.39) | DHODHNPC1RAB9AHSP90AA1HSP90AB1 | |
| Imidazole SCHEMBL6452046 | 0.83 | AMY1A (0.37) | DHODHNPC1RAB9A | |
| SCHEMBL1480794 | 0.82 | MAPT (0.40) | NPC1RAB9AHSP90AA1HSP90AB1TUBB4A | |
| SCHEMBL1480791 | 0.82 | MAPT (0.40) | NPC1RAB9AHSP90AA1HSP90AB1TUBB4A | |
| SCHEMBL6533923 | 0.78 | ITGB2 (0.42) | DHODHNPC1RAB9A | |
| SCHEMBL6533921 | 0.78 | ITGB2 (0.42) | DHODHNPC1RAB9A | |
| SCHEMBL1480482 | 0.78 | NPC1 (0.39) | NPC1RAB9AHSP90AA1HSP90AB1TUBB4A | |
| SCHEMBL1482813 | 0.78 | MEN1 (0.46) | NPC1RAB9AHSP90AA1HSP90AB1 | |
| SCHEMBL1480478 | 0.78 | NPC1 (0.39) | NPC1RAB9AHSP90AA1HSP90AB1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071447-A9 | SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS | TRANSTECH PHARMA INC (US) | 2005-10-13 | — | — | WO | disclosed |