SCHEMBL6469474

SCHEMBL6469474

CCCCP(=O)(C(=O)c1c(C(C)C)cc(C(C)C)cc1C(C)C)C(=O)c1c(C(C)C)cc(C(C)C)cc1C(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP3 P05413 2/20 0.49
FABP4 P15090 2/20 0.49
FABP5 Q01469 1/20 0.37
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
RXRA P19793 2/20 0.34
PPARG P37231 2/20 0.34
RARG P13631 1/20 0.34
RARA P10276 1/20 0.34
RARB P10826 1/20 0.34
RXRB P28702 1/20 0.34
RXRG P48443 1/20 0.34
TRPM8 Q7Z2W7 1/20 0.33
NPC1 O15118 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MCL1 Q07820 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6470066 0.95 FABP3 (0.47) FABP3FABP4FABP5GABRA1GABRB2
SCHEMBL6469869 0.94 FABP3 (0.46) FABP3FABP4FABP5TRPM8EPHX1
SCHEMBL6466073 0.94 FABP3 (0.46) FABP3FABP4FABP5TRPM8EPHX1
SCHEMBL6470201 0.94 FABP3 (0.46) FABP3FABP4FABP5TRPM8EPHX1
SCHEMBL6470246 0.82 TRPM8 (0.34) TRPM8GAATSHR
SCHEMBL6467158 0.81 FABP3 (0.42) FABP3FABP4FABP5RXRAPPARG
SCHEMBL6468614 0.80 FABP3 (0.53) FABP3FABP4FABP5GABRA1GABRB2
SCHEMBL6470033 0.77 TRPM8 (0.37) TRPM8
SCHEMBL6469476 0.75 FABP3 (0.51) FABP3FABP4FABP5GABRA1GABRB2
SCHEMBL6470369 0.72 FABP3 (0.45) FABP3FABP4FABP5GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050096406-A1 Reactive diluents and alkyd resin coating compositions PRETOT ROGER (CH) 2005-05-05 US disclosed
US-5534559-A UNSATURATED POLYESTERS CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed