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SCHEMBL6470246

SCHEMBL6470246

CCCCP(=O)(C(=O)c1c(C(C)CC)cc(C(C)CC)cc1C(C)CC)C(=O)c1c(C(C)CC)cc(C(C)CC)cc1C(C)CC

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TRPM8 Q7Z2W7 2/20 0.34
▸ HDAC4 P56524 1/20 0.31
▸ HDAC2 Q92769 1/20 0.31
▸ HDAC8 Q9BY41 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ HTT P42858 1/20 0.31
▸ TSHR P16473 4/20 0.31
▸ ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6470033 0.94 TRPM8 (0.37) TRPM8
SCHEMBL6469474 0.82 FABP3 (0.49) TRPM8GAATSHR
SCHEMBL6470066 0.78 FABP3 (0.47) TRPM8
SCHEMBL6469869 0.77 FABP3 (0.46) TRPM8
SCHEMBL6470201 0.77 FABP3 (0.46) TRPM8
SCHEMBL6466073 0.77 FABP3 (0.46) TRPM8
SCHEMBL2497195 0.69 HPGD (0.41) LMNATSHRALDH1A1
SCHEMBL6470130 0.68 TSHR (0.34) GAATSHR
SCHEMBL6467158 0.68 FABP3 (0.42) LMNAHTTTSHRALDH1A1
SCHEMBL5703484 0.66 TSHR (0.40) HDAC4HDAC2HDAC8GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050096406-A1 Reactive diluents and alkyd resin coating compositions PRETOT ROGER (CH) 2005-05-05 — — US disclosed
US-5534559-A UNSATURATED POLYESTERS CIBA-GEIGY CORPORATION (US) 1996-07-09 — — US disclosed