Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.75 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6469421 | 0.86 | AR (1.00) | ARPLA2G2ACFTRLMNAPTGDR2 | |
| SCHEMBL6469575 | 0.80 | AR (1.00) | ARPLA2G2ALMNA | |
| SCHEMBL6469722 | 0.79 | AR (1.00) | ARPLA2G2ACFTRLMNA | |
| SCHEMBL6466355 | 0.78 | AR (1.00) | ARPLA2G2ALMNA | |
| SCHEMBL6469638 | 0.77 | AR (0.83) | ARPLA2G2ACFTRLMNA | |
| SCHEMBL6466958 | 0.77 | AR (0.68) | ARPLA2G2ACFTRLMNA | |
| SCHEMBL6465329 | 0.76 | AR (1.00) | ARLMNA | |
| SCHEMBL6887430 | 0.75 | AR (0.67) | AR | |
| SCHEMBL6469582 | 0.75 | AR (0.79) | ARPLA2G2ACFTRLMNA | |
| SCHEMBL6466983 | 0.75 | AR (0.79) | ARPLA2G2ACFTRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050101657-A1 | Pyrrole derivatives for preventing or treating cancer sensitive to hormones; administered with luteininzing hormone releasing hormone derivative | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 2005-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101657-A1 | Pyrrole derivatives for preventing or treating cancer sensitive to hormones; administered with luteininzing hormone releasing hormone derivative | SHBG, PRLHR, FSHR | AR 6/4885PLA2G2A 2489/4885F2RL3 831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.