Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 12/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6467813 | 0.80 | AR (1.00) | ARSMN1; SMN2MAPTKCNJ1KCNH2 | |
| SCHEMBL6469421 | 0.77 | AR (1.00) | ARMAPTALDH1A1 | |
| SCHEMBL6469563 | 0.75 | AR (0.75) | AR | |
| SCHEMBL6889331 | 0.74 | AR (0.67) | ARHPGDSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL6889043 | 0.74 | AR (0.59) | ARKCNJ1KCNH2 | |
| SCHEMBL29411968 | 0.71 | ALDH1A1 (0.64) | ARHPGDL3MBTL1RAB9AALDH1A1 | |
| SCHEMBL28484825 | 0.71 | ALDH1A1 (0.64) | ARHPGDL3MBTL1RAB9AALDH1A1 | |
| SCHEMBL6469722 | 0.70 | AR (1.00) | ARSMN1; SMN2MAPT | |
| SCHEMBL29829604 | 0.70 | ALDH1A1 (0.50) | ARSIGMAR1HPGDL3MBTL1RAB9A | |
| SCHEMBL27583120 | 0.69 | ALDH1A1 (0.65) | SIGMAR1HPGDL3MBTL1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |