Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.34 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 3/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752948 | 0.81 | ALOX15 (0.39) | KDM4EMAPTALOX15ALOX12EPAS1 | |
| SCHEMBL30076240 | 0.81 | ALOX15 (0.39) | KDM4EMAPTALOX15ALOX12EPAS1 | |
| SCHEMBL192255 | 0.79 | ALOX15 (0.44) | KDM4EMAPTCRHBPCRHR2ALOX15 | |
| SCHEMBL9780470 | 0.77 | ALOX15 (0.43) | KDM4EMAPTALOX15ALOX12AKR1B1 | |
| SCHEMBL806364 | 0.76 | TSHR (0.42) | SLC6A2HPGDTDP1HTR1ASLC6A4 | |
| SCHEMBL9155074 | 0.75 | ALOX15 (0.42) | KDM4EMAPTALOX15ALOX12AKR1B1 | |
| SCHEMBL9780403 | 0.75 | ALOX15 (0.42) | KDM4EMAPTALOX15ALOX12AKR1B1 | |
| SCHEMBL29588385 | 0.72 | CA1 (0.46) | KDM4EMAPTALOX15ALOX12CYP2C9 | |
| SCHEMBL7101270 | 0.72 | CA1 (0.46) | KDM4EMAPTALOX15ALOX12CYP2C9 | |
| SCHEMBL6873872 | 0.72 | KDM1A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005077868-A2 | CONGENERIC, CHLORINATED, BROMINATED AND/OR IODISED, FLUORINATED AROMATIC COMPOUNDS COMPRISING TWO BENZOL RINGS IN THEIR BASIC STRUCTURE, METHOD FOR THEIR PRODUCTION AND USE THEREOF | CHIRON AS (NO) | 2005-08-25 | — | — | WO | disclosed |