Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17254460 | 0.83 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL11494758 | 0.80 | GAA (0.38) | TSHRALDH1A1MAPTGAARGS12 | |
| SCHEMBL11883738 | 0.80 | TSHR (0.35) | TSHRALDH1A1MAPTGAAMEN1 | |
| Formaldehyde SCHEMBL8154204 | 0.73 | ALDH1A1 (0.48) | TSHRALDH1A1MAPTGAAMEN1 | |
| SCHEMBL13127159 | 0.72 | — | — | |
| SCHEMBL3453860 | 0.72 | — | — | |
| SCHEMBL4228851 | 0.72 | — | — | |
| SCHEMBL11352404 | 0.71 | TSHR (0.46) | TSHRALDH1A1MAPTGAARGS12 | |
| SCHEMBL25132278 | 0.71 | GAA (0.41) | TSHRALDH1A1MAPTGAARGS12 | |
| SCHEMBL11192625 | 0.71 | ALDH1A1 (0.53) | ALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664796-B1 | METHOD OF PREPARING AMINOALKYLHYDANTOINS AND AMINOALKYL-ALPHA-AMINOACIDS | DEGUSSA (DE) | 1997-08-06 | — | — | EP | claimed |
| US-5608076-A | Method of preparing amionoakylhydantoins and aminoalkyl-alpha-amino acids | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | claimed |
| EP-1171423-B1 | CARBAMIC ACID DERIVATIVES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR LIGANDS | HOFFMANN LA ROCHE (CH) | 2005-01-12 | — | — | EP | disclosed |
| US-5608076-A | Method of preparing amionoakylhydantoins and aminoalkyl-alpha-amino acids | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |
| US-5608076-A | Method of preparing amionoakylhydantoins and aminoalkyl-alpha-amino acids | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |