Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465353 | 0.86 | NPC1 (0.37) | HPGDNPC1RAB9AHTTMAPK1 | |
| SCHEMBL275128 | 0.83 | KMT2A (0.38) | HPGDMAPK1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14570826 | 0.78 | HPGD (0.35) | HPGDMAPK1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6469681 | 0.77 | PTPN1 (0.37) | HPGDRAB9APLK1HIF1A | |
| SCHEMBL5995419 | 0.77 | KMT2A (0.37) | HPGDNPC1RAB9ANPSR1SMN1; SMN2 | |
| SCHEMBL5994287 | 0.76 | HMGCR (0.35) | HPGDRAB9AALDH1A1TSHRCYP1A2 | |
| SCHEMBL5997007 | 0.75 | KDM4E (0.36) | HPGDRAB9ANPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5996351 | 0.75 | TRPM8 (0.38) | HPGDNPSR1SMN1; SMN2FFAR1ALDH1A1 | |
| SCHEMBL5994972 | 0.75 | KMT2A (0.37) | HPGDHTTNPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5994453 | 0.74 | TRPM8 (0.44) | HPGDNPSR1SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050096406-A1 | Reactive diluents and alkyd resin coating compositions | PRETOT ROGER (CH) | 2005-05-05 | — | — | US | disclosed |
| US-5534559-A | UNSATURATED POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |