Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.61 |
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14393598 | 0.88 | MAPT (0.66) | MAOAMAOBMAPTSMN1; SMN2LIN28A | |
| SCHEMBL21844998 | 0.86 | SMN1; SMN2 (0.58) | MAOAMAOBMAPTSMN1; SMN2LIN28A | |
| SCHEMBL15372110 | 0.82 | CYP2C19 (0.50) | MAOAMAOBMAPTSMN1; SMN2LIN28A | |
| SCHEMBL11890710 | 0.82 | MAPT (0.50) | MAOAMAOBMAPTSMN1; SMN2LIN28A | |
| SCHEMBL4842263 | 0.80 | MAOA (0.71) | MAOAMAOBTDP1L3MBTL1NPC1 | |
| SCHEMBL14005755 | 0.80 | MAPT (0.51) | MAPTSMN1; SMN2LIN28ATDP1L3MBTL1 | |
| SCHEMBL21845051 | 0.80 | RAB9A (0.53) | MAPTSMN1; SMN2LIN28ATDP1L3MBTL1 | |
| SCHEMBL16805287 | 0.80 | MAPT (0.54) | MAOAMAOBMAPTSMN1; SMN2LIN28A | |
| SCHEMBL16568175 | 0.79 | SMN1; SMN2 (0.66) | MAOAMAOBMAPTSMN1; SMN2LIN28A | |
| Hydrochloric Acid SCHEMBL4843995 | 0.79 | MAOA (0.69) | MAOAMAOBTDP1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129137-B2 | Two-photon probe for real-time monitoring of intracellular free zinc ions, method for preparing the probe and method for real-time monitoring of intracellular free zinc ions using the probe | KOREA UNIVERSITY INDUSTRIAL & ACADEMIC COLLABORATION FOUNDATION (KR) | 2012-03-06 | — | — | US | disclosed |
| US-8129137-B2 | Two-photon probe for real-time monitoring of intracellular free zinc ions, method for preparing the probe and method for real-time monitoring of intracellular free zinc ions using the probe | KOREA UNIVERSITY INDUSTRIAL & ACADEMIC COLLABORATION FOUNDATION (KR) | 2012-03-06 | — | — | US | disclosed |
| US-20090286275-A1 | Two-photon probe for real-time monitoring of intracellular free zinc ions, method for preparing the probe and method for real-time monitoring of intracellular free zinc ions using the probe | SFC CO., LTD. (KR) | 2009-11-19 | — | — | US | disclosed |
| US-20090286275-A1 | Two-photon probe for real-time monitoring of intracellular free zinc ions, method for preparing the probe and method for real-time monitoring of intracellular free zinc ions using the probe | SFC CO., LTD. (KR) | 2009-11-19 | — | — | US | disclosed |
| EP-2119456-A1 | Two-photon probe for real-time monitoring of intracellular free zinc ions, method for preparing the probe and method for real-time monitoring of intracellular free zinc ions using the probe | Korea University Industrial & Academic Collaboration Foundation (KR) | 2009-11-18 | — | — | EP | disclosed |
| US-RE40572-E1 | Fluorescent probe for the quantitation of zinc | SEKISUI MEDICAL CO., LTD. (JP) | 2008-11-11 | — | — | US | disclosed |
| US-RE40572-E1 | Fluorescent probe for the quantitation of zinc | SEKISUI MEDICAL CO., LTD. (JP) | 2008-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286275-A1 | Two-photon probe for real-time monitoring of intracellular free zinc ions, method for preparing the probe and method for real-time monitoring of intracellular free zinc ions using the probe | SLC39A3, SLC30A7, SLC39A7 | MAOA 3523/4885MAOB 2505/4885MAPT 3270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.