Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6469931 | 0.95 | APP (0.56) | KCNA3APPMGLLCHRNA7LMNA | |
| SCHEMBL17784340 | 0.93 | MGLL (0.58) | KCNA3MGLLCHRNA7LMNACYP1A2 | |
| SCHEMBL17784357 | 0.93 | MGLL (0.58) | KCNA3MGLLCHRNA7LMNACYP1A2 | |
| SCHEMBL17784369 | 0.93 | MGLL (0.58) | KCNA3MGLLCHRNA7LMNACYP1A2 | |
| SCHEMBL17784350 | 0.93 | MGLL (0.58) | KCNA3MGLLCHRNA7LMNACYP1A2 | |
| SCHEMBL95473 | 0.87 | KCNA3 (0.76) | KCNA3HDAC6LTA4HALDH1A1 | |
| SCHEMBL4161955 | 0.85 | FOXM1 (0.54) | APPMGLLCHRNA7LMNACYP1A2 | |
| SCHEMBL8501296 | 0.85 | KCNA3 (0.73) | KCNA3HDAC6LTA4HALDH1A1 | |
| SCHEMBL94687 | 0.85 | KCNA3 (0.73) | KCNA3HDAC6LTA4HALDH1A1 | |
| SCHEMBL8495999 | 0.85 | KCNA3 (0.73) | KCNA3HDAC6LTA4HALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107468-A1 | Process for the preparation of an enantiomerically enriched thio compound | DSM IP ASSETS B.V. (NL) | 2005-05-19 | — | — | US | disclosed |
| EP-1453797-A1 | PROCESS FOR THE PREPARATION OF AN ENANTIOMERICALLY ENRICHED THIO COMPOUND | DSM IP Assets B.V. (NL) | 2004-09-08 | — | — | EP | disclosed |
| EP-1325908-A1 | Process for the preparation of an enantiomerically enriched thio compound | DSM N.V. (NL) | 2003-07-09 | — | — | EP | disclosed |
| WO-2003051827-A1 | PROCESS FOR THE PREPARATION OF AN ENANTIOMERICALLY ENRICHED THIO COMPOUND | DSM IP ASSETS B.V. (NL) | 2003-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107468-A1 | Process for the preparation of an enantiomerically enriched thio compound | SLC7A1, TCP1, TFRC | KCNA3 2244/4885APP 4488/4885MGLL 4097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.