Fluoride

Fluoride

SCHEMBL6469969

COCCOC.F.F.F.F

nearest known ligand 0.32

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Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32
PIK3CD O00329 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CA2 P00918 2/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL4798641 1.00
Fluoride SCHEMBL6469965 1.00 TSHR (0.32) TSHRPIK3CDALDH1A1CA2KDM4E
SCHEMBL1154 0.94
SCHEMBL251442 0.94 ALDH1A1 (0.33) TSHRPIK3CDALDH1A1CA2KDM4E
SCHEMBL11864412 0.89
SCHEMBL15674477 0.89
Hydrochloric Acid SCHEMBL7542079 0.89 TSHR (0.32) TSHRPIK3CDALDH1A1CA2KDM4E
SCHEMBL15821191 0.89
Water SCHEMBL337744 0.89 TSHR (0.32) TSHRPIK3CDALDH1A1CA2KDM4E
SCHEMBL18304645 0.89 TSHR (0.32) TSHRPIK3CDALDH1A1CA2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0955305-B1 Metallocene compound, and process for preparing polyolefin by using it MITSUI CHEMICALS INC (JP) 2005-10-26 EP disclosed