SCHEMBL6470185

SCHEMBL6470185

CCc1c(O)ccc(O)c1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.39
PRKCI P41743 1/20 0.36
ALDH1A1 P00352 3/20 0.35
ALOX15 P16050 2/20 0.35
HSD17B10 Q99714 2/20 0.35
GAA P10253 2/20 0.35
BACE1 P56817 1/20 0.35
USP2 O75604 1/20 0.35
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.35
ACHE P22303 1/20 0.35
ESR1 P03372 7/20 0.35
ESR2 Q92731 7/20 0.35
PDE10A Q9Y233 1/20 0.34
NOS3 P29474 1/20 0.34
NOS2 P35228 1/20 0.34
AR P10275 1/20 0.33
USP7 Q93009 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29211012 0.86 ESR1 (0.39) TRPA1PRKCIALDH1A1ALOX15HSD17B10
SCHEMBL23804830 0.86 ESR1 (0.39) TRPA1PRKCIALDH1A1ALOX15HSD17B10
SCHEMBL30478808 0.84 PDE10A (0.45) ALDH1A1ALOX15HSD17B10ESR1ESR2
SCHEMBL5823114 0.84 BACE1 (0.40) TRPA1PRKCIBACE1ACHEESR1
SCHEMBL2423001 0.84 NOS3 (0.44) TRPA1ALDH1A1ALOX15HSD17B10GAA
SCHEMBL652985 0.84 BACE1 (0.40) TRPA1PRKCIBACE1ACHEESR1
SCHEMBL3685532 0.82 CA1 (0.39) TRPA1PRKCIALDH1A1ALOX15HSD17B10
SCHEMBL29178121 0.82 ESR1 (0.37) TRPA1PRKCIBACE1ESR1ESR2
SCHEMBL858277 0.81 TRPA1 (0.48) TRPA1ALDH1A1HSD17B10GAABACE1
SCHEMBL30026897 0.81 TRPA1 (0.48) TRPA1ALDH1A1HSD17B10GAABACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1534225-A1 METHOD OF COLOURING POROUS MATERIAL Ciba Specialty Chemicals Holding Inc. (CH) 2005-06-01 EP disclosed
WO-2004019896-A1 METHOD OF COLOURING POROUS MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-03-11 WO disclosed