Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | FDPS | P14324 | 3/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9421435 | 1.00 | TSHR (0.50) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL9720163 | 0.87 | DNM1 (0.45) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL9208085 | 0.86 | OPRM1 (0.46) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL28277590 | 0.86 | OPRM1 (0.46) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL28153717 | 0.86 | OPRM1 (0.46) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL21052487 | 0.86 | OPRM1 (0.46) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL11718763 | 0.86 | OPRM1 (0.46) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL28154764 | 0.86 | OPRM1 (0.46) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL21052334 | 0.86 | OPRM1 (0.46) | TSHRTHRBLMNADNM1OPRM1 | |
| SCHEMBL28154761 | 0.86 | OPRM1 (0.46) | TSHRTHRBLMNADNM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592664-A1 | GRAFTABLE HINDERED AMINE LIGHT STABILIZERS | Ciba SC Holding AG (CH) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004072035-A1 | GRAFTABLE HINDERED AMINE LIGHT STABILIZERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-08-26 | — | — | WO | disclosed |