Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670723 | 0.94 | TSHR (0.41) | TSHRALDH1A1TDP1LOXLOXL3 | |
| SCHEMBL29154624 | 0.94 | ALDH1A1 (0.46) | TSHRALDH1A1TDP1LOXLOXL3 | |
| SCHEMBL8011581 | 0.85 | — | — | |
| SCHEMBL8723146 | 0.85 | — | — | |
| SCHEMBL11071480 | 0.85 | ALDH1A1 (0.43) | TSHRALDH1A1TDP1LOXLOXL3 | |
| SCHEMBL14110162 | 0.83 | TSHR (0.56) | TSHRCYP3A4 | |
| SCHEMBL17982757 | 0.80 | TSHR (0.45) | TSHRALDH1A1TDP1LOXLOXL3 | |
| SCHEMBL17982758 | 0.80 | TSHR (0.45) | TSHRALDH1A1TDP1LOXLOXL3 | |
| SCHEMBL4521386 | 0.79 | — | — | |
| SCHEMBL15821306 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |