Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL713795 | 0.92 | BCHE (0.35) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL6470828 | 0.90 | GPR3 (0.31) | GPR3 | |
| Hydrochloric Acid SCHEMBL6472198 | 0.90 | BCHE (0.34) | BCHEACHEGPR3 | |
| Hydrochloric Acid SCHEMBL6472415 | 0.90 | BCHE (0.34) | BCHEACHEGPR3 | |
| Hydrochloric Acid SCHEMBL6470589 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL714779 | 0.80 | GPR3 (0.33) | GPR3 | |
| Hydrochloric Acid SCHEMBL714799 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL1116209 | 0.72 | BCHE (0.33) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL6473194 | 0.72 | CYP2D6 (0.31) | — | |
| Hydrochloric Acid SCHEMBL6471681 | 0.72 | CYP2D6 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6870015-B2 | Catalyst component for addition polymerization, process for producing catalyst for addition polymerization and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-03-22 | — | — | US | disclosed |
| EP-1300425-A2 | Catalyst component for addition polymerization, process for producing said catalyst and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-20030060579-A1 | Catalyst component for addition polymerization, process for producing catalyst for addition polymerization and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-03-27 | — | — | US | disclosed |