SCHEMBL6470484

SCHEMBL6470484

CCC(OC)(c1ccccc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
KCNN4 O15554 5/20 0.41
MAPK1 P28482 1/20 0.41
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CES1 P23141 1/20 0.39
ALDH1A1 P00352 2/20 0.38
TAAR1 Q96RJ0 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX5 P09917 3/20 0.36
GAA P10253 1/20 0.36
TP53 P04637 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7764290 0.83 KCNN4 (0.43) LMNAKCNN4MAPK1ALDH1A1TAAR1
SCHEMBL29280866 0.83 MAPK1 (0.48) LMNAKCNN4MAPK1ALDH1A1TAAR1
SCHEMBL8820311 0.83 LMNA (0.41) LMNAKCNN4MAPK1KDM4EMEN1
SCHEMBL15357624 0.81 LMNA (0.44) LMNAKCNN4MAPK1KDM4EMEN1
SCHEMBL11750519 0.81 LMNA (0.41) LMNAMEN1KMT2AALDH1A1GAA
Hydrochloric Acid SCHEMBL27457472 0.81 LMNA (0.42) LMNAKCNN4MAPK1KDM4EMEN1
SCHEMBL6057047 0.79 LMNA (0.45) LMNAKCNN4MAPK1KDM4EMEN1
SCHEMBL22788269 0.79 KCNN4 (0.40) LMNAKCNN4MAPK1ALDH1A1TAAR1
SCHEMBL2238102 0.79 KCNN4 (0.40) LMNAKCNN4MAPK1ALDH1A1TAAR1
SCHEMBL3950657 0.79 KCNN4 (0.40) LMNAKCNN4MAPK1ALDH1A1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102047181-B Photosensitive resin composition ASAHI KASEI E MATERIALS CORP 2013-01-23 CN disclosed
CN-102047181-A Photosensitive resin composition ASAHI KASEI E MATERIALS CORP 2011-05-04 CN disclosed
US-20100256329-A1 STEREOSELECTIVE ALTERNATING COPOLYMERIZATION OF EPOXIDE WITH CARBON DIOXIDE THE UNIVERSITY OF TOKYO (JP) 2010-10-07 US disclosed
US-7172855-B2 Silver halide photographic light-sensitive material and package thereof FUJI PHOTO FILM CO., LTD. (JP) 2007-02-06 US disclosed
US-20050197350-A1 Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof TAISHO PHARMACEUTICAL CO., LTD. 2005-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050197350-A1 Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof HCRTR2, MCHR1, MCHR2 LMNA 3391/4885KCNN4 1683/4885MAPK1 2507/4885
US-20100256329-A1 STEREOSELECTIVE ALTERNATING COPOLYMERIZATION OF EPOXIDE WITH CARBON DIOXIDE PCNA, HPD, TET3 LMNA 3481/4885KCNN4 2645/4885MAPK1 3529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.