Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | CTSV | O60911 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20819599 | 0.88 | MAPT (0.56) | PTGER1NPC1MRGPRX4LMNAMAPT | |
| SCHEMBL9650260 | 0.87 | FOLH1 (0.56) | PTGER1NPC1MRGPRX4LMNAMAPT | |
| SCHEMBL8303386 | 0.86 | HTT (0.58) | PTGER1NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL20819560 | 0.85 | NPC1 (0.53) | PTGER1NPC1MRGPRX4LMNAMAPT | |
| SCHEMBL112903 | 0.84 | SGMS2 (0.66) | PTGER1NPC1LMNAMAPTL3MBTL1 | |
| SCHEMBL29433417 | 0.84 | SGMS2 (0.66) | PTGER1NPC1LMNAMAPTL3MBTL1 | |
| Bicarbonate SCHEMBL236872 | 0.83 | SGMS2 (0.64) | PTGER1NPC1LMNAMAPTL3MBTL1 | |
| Bicarbonate SCHEMBL21753662 | 0.83 | SGMS2 (0.64) | PTGER1NPC1LMNAMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8998291 | 0.83 | SGMS2 (0.64) | PTGER1NPC1LMNAMAPTL3MBTL1 | |
| Bicarbonate SCHEMBL29914194 | 0.83 | SGMS2 (0.64) | PTGER1NPC1LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794526-A | Compositions and methods for antioxidants and anti-inflammatory therapeutics | 阿万蒂生物科学股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| EP-1515926-A2 | FLUOROBENZAMIDES SUITABLE FOR THE TREATMENT OF ALZHEIMER'S DISEASE OR SENILE DEMENTIA | F.HOFFMANN-LA ROCHE AG (CH) | 2005-03-23 | — | — | EP | disclosed |
| WO-2003106380-A2 | FLUOROBENZAMIDES | F.HOFFMANN-LA ROCHE AG (CH) | 2003-12-24 | — | — | WO | disclosed |
| CN-1087291-C | N-hydroxyureas as anti-inflammatory agents | PFIZER (US) | 2002-07-10 | — | — | CN | disclosed |
| EP-0832078-B1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER (US) | 1999-10-20 | — | — | EP | disclosed |
| US-5814648-A | N-hydroxyureas as antiinflammatory agents | PFIZER INC. (US) | 1998-09-29 | — | — | US | disclosed |
| CN-1191531-A | N-hydroxyureas as antiinflammatory agents | PFIZER (US) | 1998-08-26 | — | — | CN | disclosed |
| EP-0832078-A1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040659-A1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1996-12-19 | — | — | WO | disclosed |