Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MAOA | P21397 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | C1R | P00736 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TOP2A | P11388 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5842491 | 0.85 | MAOA (0.51) | KDM4EMAOAMAPTHSD17B10CYP3A4 | |
| SCHEMBL3397900 | 0.80 | TOP2A (0.41) | KDM4EMAOAALDH1A1MAPTHSD17B10 | |
| SCHEMBL29440787 | 0.76 | AKR1C3 (0.54) | KDM4EMAOANPC1RAB9AMAPT | |
| SCHEMBL29440785 | 0.76 | AKR1C3 (0.54) | KDM4EMAOANPC1RAB9AMAPT | |
| SCHEMBL61277 | 0.76 | AKR1C3 (0.54) | KDM4EMAOANPC1RAB9AMAPT | |
| SCHEMBL12228494 | 0.74 | MAPT (0.57) | KDM4EMAOAALDH1A1NPC1RAB9A | |
| SCHEMBL6469873 | 0.73 | NPC1 (0.52) | KDM4EMAOAALDH1A1NPC1RAB9A | |
| SCHEMBL5844099 | 0.73 | MAOA (0.52) | KDM4EMAOAALDH1A1NPC1RAB9A | |
| SCHEMBL30346412 | 0.71 | MAOA (0.79) | KDM4EMAOAALDH1A1NPC1RAB9A | |
| SCHEMBL8811366 | 0.71 | KDM4E (0.58) | KDM4EMAOAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050235428-A1 | Use of metal complex compounds as oxidation catalysts | CIBA SPECIALTY CHEMICALS CORP. | 2005-10-27 | — | — | US | disclosed |
| EP-1456216-A1 | USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | Ciba SC Holding AG (CH) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053986-A1 | USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-07-03 | — | — | WO | disclosed |