Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468938 | 0.90 | KMT2A (0.58) | KMT2AMEN1CA2MMP2CA1 | |
| SCHEMBL6025519 | 0.82 | KMT2A (0.49) | KMT2AMEN1CA2MMP2CA1 | |
| SCHEMBL6533316 | 0.79 | KMT2A (0.49) | KMT2AMEN1CA2MMP2CA1 | |
| SCHEMBL6026285 | 0.78 | KMT2A (0.47) | KMT2AMEN1CA2MMP2CA1 | |
| SCHEMBL6531285 | 0.77 | KMT2A (0.46) | KMT2AMEN1CA2MMP2CA1 | |
| SCHEMBL1701616 | 0.77 | CA2 (0.67) | KMT2AMEN1CA2MMP2CA1 | |
| SCHEMBL2034554 | 0.76 | KMT2A (0.78) | KMT2AMEN1CA2MMP2CA1 | |
| SCHEMBL922441 | 0.76 | KMT2A (0.77) | KMT2AMEN1CA2MMP2CA1 | |
| SCHEMBL17526270 | 0.76 | CA2 (0.66) | KMT2AMEN1CA2MMP2CA1 | |
| SCHEMBL7681888 | 0.75 | KMT2A (0.71) | KMT2AMEN1CA2MMP2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005049593-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2005-06-02 | — | — | WO | disclosed |