Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 12/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533063 | 0.89 | MAPK14 (0.42) | MAPK14MAPK11MAOBPTGES | |
| SCHEMBL6471529 | 0.88 | MAPK14 (0.40) | MAPK14MAPK11MAOBPTGES | |
| SCHEMBL6471273 | 0.87 | MAPK14 (0.44) | MAPK14MAOBPTGESMEN1KMT2A | |
| SCHEMBL6470956 | 0.86 | MAPK14 (0.44) | MAPK14L3MBTL1MAOBPTGESMEN1 | |
| SCHEMBL6473625 | 0.84 | HTR2A (0.38) | MAPK14MAOB | |
| SCHEMBL6471570 | 0.82 | KMT2A (0.39) | MAPK14MEN1KMT2A | |
| SCHEMBL6472774 | 0.80 | HTR2A (0.36) | MAPK14 | |
| SCHEMBL6471156 | 0.79 | MAPK14 (0.41) | MAPK14MAOB | |
| SCHEMBL6472250 | 0.76 | MAPK14 (0.40) | MAPK14MAOBIDO1 | |
| SCHEMBL4478238 | 0.74 | MAPK14 (0.49) | MAPK14MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |