Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.42 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471529 | 0.90 | MAPK14 (0.40) | MAPK14RETMAOBPTGESBRD4 | |
| SCHEMBL6470939 | 0.89 | MAPK14 (0.41) | MAPK14MAOBPTGESMAPK11 | |
| SCHEMBL6471273 | 0.88 | MAPK14 (0.44) | MAPK14MAOBPTGES | |
| SCHEMBL6470956 | 0.87 | MAPK14 (0.44) | MAPK14RETMAOBPTGES | |
| SCHEMBL6471570 | 0.83 | KMT2A (0.39) | MAPK14 | |
| SCHEMBL6473625 | 0.80 | HTR2A (0.38) | MAPK14MAOB | |
| SCHEMBL6472887 | 0.79 | MAPK14 (0.44) | MAPK14PTGES | |
| SCHEMBL6471156 | 0.79 | MAPK14 (0.41) | MAPK14MAOB | |
| SCHEMBL6472250 | 0.76 | MAPK14 (0.40) | MAPK14MAOBBRD4 | |
| SCHEMBL6472774 | 0.76 | HTR2A (0.36) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |