Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL27831923 | 0.97 | TSHR (0.35) | TSHRACHELMNAALOX12ALDH1A1 | |
| Bromide SCHEMBL28517862 | 0.97 | TSHR (0.35) | TSHRACHELMNAALOX12ALDH1A1 | |
| Bromide SCHEMBL16741147 | 0.97 | TSHR (0.35) | TSHRACHELMNAALOX12ALDH1A1 | |
| Bromide SCHEMBL28008326 | 0.97 | TSHR (0.35) | TSHRACHELMNAALOX12ALDH1A1 | |
| SCHEMBL8952 | 0.97 | TSHR (0.39) | TSHRACHELMNAALOX12ALDH1A1 | |
| SCHEMBL2789002 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6778262 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 | |
| Phosphine SCHEMBL5003432 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 | |
| SCHEMBL17431672 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 | |
| Iodide SCHEMBL2117427 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 843 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122059990-A | Force-induced luminescence hybrid crystalline material | 温州锌芯钛晶科技有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122010689-A | Preparation method of cycloparaffin | 浙江清华长三角研究院 | 2026-05-12 | — | — | CN | claimed |
| CN-122011262-A | Polymer synthetic resin type building curtain wall material and preparation method thereof | 广州博为建科工程有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-120192289-A | Synthesis method of multi-functional 2-alkenyl furan-ring-4-ketone and 5-alkenyl-3-furan carbonyl compound | 首都医科大学 | 2025-06-24 | — | — | CN | claimed |
| CN-120201852-A | Perovskite battery and preparation method thereof, laminated battery and photovoltaic module | 晶科能源股份有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-120079244-A | Loose nanofiltration membrane and preparation method thereof | 山东中康国创先进印染技术研究院有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-120040978-A | Flexible bio-based glass material with adjustable optical properties and preparation method thereof | 北京师范大学 | 2025-05-27 | — | — | CN | claimed |
| CN-119979084-A | Underfill with high Tg and low expansion coefficient and preparation method thereof | 矽时代材料科技股份有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119930444-A | Ozone resisting agent for rubber, preparation method and application thereof, and rubber | 株洲时代新材料科技股份有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119786575-A | Sodium iron sulfate composite material and preparation method and application thereof | 深圳先进技术研究院 | 2025-04-08 | — | — | CN | claimed |
| CN-113754701-A | Iridium ferrocene pyridine complex with semi-sandwich structure and preparation method and application thereof | 曲阜师范大学 | 2021-12-07 | — | — | CN | claimed |
| CN-113583168-A | High-activity copolymer with controllable dispersed sequences of 1,1-diphenylethylene derivatives and styrene and preparation method thereof | 大连理工大学 | 2021-11-02 | — | — | CN | claimed |
| CN-113314777-A | Recovery method of solid battery material | 中国科学院化学研究所 | 2021-08-27 | — | — | CN | claimed |
| CN-112755964-A | Active carbon desulfurizer loaded with quaternary phosphorus-based eutectic solvent and preparation and use methods thereof | 辽宁科技大学 | 2021-05-07 | — | — | CN | claimed |
| CN-112424286-A | Polyester resin composition and preparation method and application thereof | 擎天材料科技有限公司 | 2021-02-26 | — | — | CN | claimed |
| CN-108727256-B | Photosensitizer based on triphenylamine polypyridine salt and preparation method and application thereof | 华中科技大学 | 2020-07-07 | — | — | CN | claimed |
| US-20090076142-A1 | USE OF THE IRRITATING PRINCIPAL OLEOCANTHAL IN OLIVE OIL, AS WELL AS STRUCTURALLY AND FUNCTIONALLY SIMILAR COMPOUNDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2009-03-19 | — | — | US | claimed |
| EP-1888091-A2 | USE OF THE IRRITATING PRINCIPAL OLEOCANTHAL IN OLIVE OIL, AS WELL AS STRUCTURALLY AND FUNCTIONALLY SIMILAR COMPOUNDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-02-20 | — | — | EP | claimed |
| WO-2006122128-A2 | USE OF THE IRRITATING PRINCIPAL OLEOCANTHAL IN OLIVE OIL, AS WELL AS STRUCTURALLY AND FUNCTIONALLY SIMILAR COMPOUNDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-11-16 | — | — | WO | claimed |
| CN-1807409-A | Thioamide analog compound synthesis method | ZHU KAIQIN (CN) | 2006-07-26 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076142-A1 | USE OF THE IRRITATING PRINCIPAL OLEOCANTHAL IN OLIVE OIL, AS WELL AS STRUCTURALLY AND FUNCTIONALLY SIMILAR COMPOUNDS | OXER1, TRPA1, NR1H3 | ACHE 1033/4885TSHR 1462/4885LMNA 4521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.