Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.37 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.31 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.30 |
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27934154 | 1.00 | TSHR (0.37) | TSHRACHELMNAALOX12TDP1 | |
| SCHEMBL8952 | 0.97 | TSHR (0.39) | TSHRACHELMNAALOX12TDP1 | |
| Bromide SCHEMBL647163 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12TDP1 | |
| SCHEMBL16034408 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12TDP1 | |
| Water SCHEMBL29155020 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12TDP1 | |
| Phosphine SCHEMBL5003432 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12TDP1 | |
| SCHEMBL2789002 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12TDP1 | |
| SCHEMBL17431672 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12TDP1 | |
| Iodide SCHEMBL2117427 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12TDP1 | |
| SCHEMBL8967804 | 0.93 | TSHR (0.37) | TSHRACHELMNAALOX12TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122059990-A | Force-induced luminescence hybrid crystalline material | 温州锌芯钛晶科技有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122010689-A | Preparation method of cycloparaffin | 浙江清华长三角研究院 | 2026-05-12 | — | — | CN | claimed |
| CN-120040978-A | Flexible bio-based glass material with adjustable optical properties and preparation method thereof | 北京师范大学 | 2025-05-27 | — | — | CN | claimed |
| CN-119930444-A | Ozone resisting agent for rubber, preparation method and application thereof, and rubber | 株洲时代新材料科技股份有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119725728-A | Ether electrolyte additive and application thereof in sodium ion battery | 中国科学院大连化学物理研究所 | 2025-03-28 | — | — | CN | claimed |
| CN-119555859-A | High-sensitivity high-flux identification method for saccharide compounds based on chlorine enhanced ionization | 北京大学 | 2025-03-04 | — | — | CN | claimed |
| CN-119285533-A | Preparation method of key intermediate of lysine-specific demethylase 1 (LSD 1) inhibitor | 江苏联环药业股份有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-118878609-A | Green synthesis method of dydrogesterone and intermediate thereof | 菏泽皓元医药科技有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-113880694-B | Synthesis method of hydroxy-substituted styrene compound and synthesis method of photoresist resin monomer | 徐州博康信息化学品有限公司 | 2024-09-13 | — | — | CN | claimed |
| CN-113801063-B | 1- (4-Carboxyperoxybenzyl) -3-methylimidazole aluminum tetrachloride salt or iron salt, and preparation and application thereof | 浙江工业大学 | 2024-07-30 | — | — | CN | claimed |
| CN-118290228-A | Preparation method of aforana key intermediate | 长沙创新药物工业技术研究院有限公司 | 2024-07-05 | — | — | CN | claimed |
| WO-2024082090-A1 | MANGANESE-BASED SCINTILLATION CRYSTALLINE MATERIAL, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 闽都创新实验室 | 2024-04-25 | — | — | WO | claimed |
| CN-117899944-A | Catalyst for synthesizing chloroethylene by acetylene liquid phase, preparation method and application thereof | 鄂尔多斯市瀚博科技有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-117362164-A | Photoresist monomer compound and preparation method and application thereof | 中节能万润股份有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-115160202-B | Preparation method of carboprost tromethamine and intermediate thereof | 广州楷石医药有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-116265430-A | Preparation method and application of p-toluenesulfonate low-halogen deep eutectic solvent | 华东理工大学 | 2023-06-20 | — | — | CN | claimed |
| CN-114230434-A | Method for producing trichlorobenzyl by directional chlorination of alkylbenzene and trichlorobenzyl | 河南特格纳特科技有限公司 | 2022-03-25 | — | — | CN | claimed |
| CN-111393621-A | Corrosion-resistant polyester resin and preparation method thereof | 黄山泰鑫新材料有限公司 | 2020-07-10 | — | — | CN | claimed |
| CN-122059990-A | Force-induced luminescence hybrid crystalline material | 温州锌芯钛晶科技有限公司 | 2026-05-19 | — | — | CN | disclosed |
| EP-0214556-A1 | Substituted hexahydro-arylquinolizine derivatives, processes for their preparation and pharmaceutical composition containing them | MERCK & CO. INC. (US) | 1987-03-18 | — | — | EP | disclosed |