Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 10/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471283 | 0.91 | PDE3B (0.37) | PTGER1MAPK14MAOB | |
| SCHEMBL6471998 | 0.90 | MAPK14 (0.43) | PTGER1MAPK14 | |
| SCHEMBL6473806 | 0.87 | MAPK14 (0.37) | PTGER1MAPK14 | |
| SCHEMBL6470897 | 0.85 | MAPK14 (0.37) | PTGER1MAPK14 | |
| SCHEMBL6471580 | 0.82 | MAPK14 (0.45) | PTGER1MAPK14MAOB | |
| SCHEMBL6471970 | 0.81 | MAPK14 (0.44) | PTGER1MAPK14 | |
| SCHEMBL6473585 | 0.80 | MAPK14 (0.41) | PTGER1MAPK14 | |
| SCHEMBL6472398 | 0.80 | MAPK14 (0.43) | PTGER1MAPK14 | |
| SCHEMBL6474519 | 0.78 | MAPK14 (0.46) | MAPK14 | |
| SCHEMBL6471522 | 0.78 | MAPK14 (0.42) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |