Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30496176 | 0.78 | NR2F2 (0.41) | ALDH1A1CA2POLBTYRSMN1; SMN2 | |
| SCHEMBL13280777 | 0.78 | AKR1C4 (0.37) | ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL4751041 | 0.77 | MEN1 (0.51) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28488463 | 0.75 | HSD17B10 (0.57) | ALDH1A1NR2F2MEN1HPGDKMT2A | |
| SCHEMBL12933288 | 0.75 | HSD11B1 (0.50) | ALDH1A1SMN1; SMN2MEN1HPGDKMT2A | |
| SCHEMBL4946050 | 0.73 | MEN1 (0.54) | ALDH1A1MEN1KMT2A | |
| SCHEMBL30506530 | 0.73 | MEN1 (0.54) | ALDH1A1MEN1KMT2A | |
| SCHEMBL11559830 | 0.72 | HMGB1 (0.46) | ALDH1A1NR2F2MEN1HPGDKMT2A | |
| SCHEMBL22877704 | 0.72 | MEN1 (0.41) | POLBMEN1HPGDKMT2A | |
| SCHEMBL25243117 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6065458-A | — | — | None | — | — | JP | disclosed |
| EP-1575575-A2 | SAFE CHEMICAL UNCOUPLERS FOR THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004041256-A2 | SAFE CHEMICAL UNCOUPLERS FOR THE TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2004-05-21 | — | — | WO | disclosed |
| JP-H0665458-A | CHLORINE-CONTAINING RESIN COMPOSITION | NIPPON OIL & FATS CO LTD | 1994-03-08 | — | — | JP | disclosed |