Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162366 | 0.88 | TDP1 (0.48) | TDP1LMNAGAASMN1; SMN2KDM4E | |
| SCHEMBL6471833 | 0.87 | MTNR1A (0.45) | TDP1LMNAMTNR1AMTNR1BKDM4E | |
| SCHEMBL391346 | 0.82 | TDP1 (0.48) | TDP1LMNAGAASMN1; SMN2KDM4E | |
| SCHEMBL26412860 | 0.81 | TDP1 (0.37) | TDP1LMNAGAASMN1; SMN2KDM4E | |
| SCHEMBL7259428 | 0.81 | TDP1 (0.47) | TDP1LMNAGAASMN1; SMN2KDM4E | |
| SCHEMBL28093877 | 0.81 | TDP1 (0.47) | TDP1LMNAGAASMN1; SMN2KDM4E | |
| SCHEMBL14431528 | 0.79 | MEN1 (0.47) | SMN1; SMN2MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL1515826 | 0.78 | CYP4F2 (0.62) | TDP1LMNAGAASMN1; SMN2KDM4E | |
| SCHEMBL6916631 | 0.77 | TDP1 (0.58) | TDP1LMNAGAASMN1; SMN2KDM4E | |
| SCHEMBL3115725 | 0.77 | CYP4F2 (0.49) | TDP1LMNAGAASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019140-A1 | ETHYL 4-(2-TERT-BUTOXY-2-OXOETHYL)-2-ETHOXYBENZOATE, INTERMEDIATE FOR THE PREPARATION OF REPAGLINIDE | BIOCON LIMITED (IN) | 2005-03-03 | — | — | WO | disclosed |
| WO-2005019140-A1 | ETHYL 4-(2-TERT-BUTOXY-2-OXOETHYL)-2-ETHOXYBENZOATE, INTERMEDIATE FOR THE PREPARATION OF REPAGLINIDE | BIOCON LIMITED (IN) | 2005-03-03 | — | — | WO | disclosed |