Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909316 | 0.88 | TDP1 (0.58) | TDP1ALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL7802422 | 0.88 | TDP1 (0.64) | TDP1ALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL16954218 | 0.85 | TDP1 (0.61) | TDP1ALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL28601211 | 0.84 | ALDH1A1 (0.56) | ALDH1A1HTTSMN1; SMN2GAAGFER | |
| SCHEMBL5162366 | 0.82 | TDP1 (0.48) | TDP1ALDH1A1SMN1; SMN2GAACYP4F2 | |
| SCHEMBL24450637 | 0.82 | ALDH1A1 (0.60) | TDP1ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL18887599 | 0.82 | TSHR (0.56) | TDP1ALDH1A1SMN1; SMN2GAAKDM4E | |
| SCHEMBL21605365 | 0.81 | ALDH1A1 (0.59) | TDP1ALDH1A1HTTSMN1; SMN2GAA | |
| SCHEMBL27009292 | 0.78 | TDP1 (0.64) | TDP1ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL2847294 | 0.78 | TDP1 (0.64) | TDP1ALDH1A1HTTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040249188-A1 | Process for the preparation of 3-ethoxy-4-(alkoxy carbonyl)-phenyl acetic acid. (an intermediate of repaglinide) | DR. REDDY'S LABORATORIES LIMITED | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040249188-A1 | Process for the preparation of 3-ethoxy-4-(alkoxy carbonyl)-phenyl acetic acid. (an intermediate of repaglinide) | ALDH1A1, ADRM1, ALDH7A1 | TDP1 1135/4885ALDH1A1 1/4885HTT 1401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.