Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.57 |
| ▸ | MLYCD | O95822 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471270 | 0.87 | NPC1 (0.47) | MEN1KMT2ATDP1LMNAHPGD | |
| SCHEMBL6471331 | 0.76 | SMN1; SMN2 (0.59) | MEN1KMT2AGAATDP1LMNA | |
| SCHEMBL10389082 | 0.75 | MEN1 (0.70) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL4470067 | 0.74 | GAA (0.59) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL6472533 | 0.73 | AKR1B1 (0.40) | MEN1KMT2ARAB9A | |
| SCHEMBL23447721 | 0.73 | MLYCD (0.77) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL5227678 | 0.73 | MLYCD (0.86) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL23978884 | 0.72 | MEN1 (0.73) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL5261051 | 0.72 | MLYCD (0.80) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 | |
| SCHEMBL10389355 | 0.72 | LMNA (0.68) | MEN1KMT2APLA2G1BCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |