Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 4/20 | 0.35 |
| ▸ | CES1 | P23141 | 4/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 3/20 | 0.33 |
| ▸ | FEN1 | P39748 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | PTPRF | P10586 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6474442 | 0.91 | CES2 (0.38) | ALDH1A1MEN1KMT2ATDP1USP2 | |
| SCHEMBL6472434 | 0.91 | CES2 (0.41) | ALDH1A1MEN1KMT2ATDP1USP2 | |
| SCHEMBL6472601 | 0.89 | CES2 (0.42) | ALDH1A1MEN1KMT2ATDP1USP2 | |
| SCHEMBL6472064 | 0.89 | CES2 (0.42) | ALDH1A1MEN1KMT2ATDP1USP2 | |
| SCHEMBL6527030 | 0.82 | CNR1 (0.37) | ALDH1A1KMT2AUSP2LMNAPOLB | |
| SCHEMBL6528803 | 0.78 | MEN1 (0.41) | ALDH1A1MEN1KMT2ATDP1USP2 | |
| SCHEMBL6472113 | 0.76 | CYP1A2 (0.46) | ALDH1A1MEN1KMT2AUSP2LMNA | |
| SCHEMBL29875702 | 0.74 | MEN1 (0.53) | ALDH1A1MEN1KMT2ATDP1POLB | |
| SCHEMBL6475119 | 0.74 | CNR1 (0.36) | ALDH1A1USP2LMNAPOLBMAPT | |
| SCHEMBL6474059 | 0.71 | TAAR1 (0.46) | ALDH1A1USP2LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005109041-A1 | COMPOSITIONS FOR USE IN THE MANUFACTURE OF LENSES | MEDICAL POLYMERS LIMITED (GB) | 2005-11-17 | — | — | WO | disclosed |