Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472601 | 1.00 | CES2 (0.42) | CES2CES1TDP1MEN1KMT2A | |
| SCHEMBL6472434 | 0.98 | CES2 (0.41) | CES2CES1TDP1MEN1KMT2A | |
| SCHEMBL6474442 | 0.95 | CES2 (0.38) | CES2CES1TDP1MEN1KMT2A | |
| SCHEMBL6472071 | 0.89 | ALDH1A1 (0.40) | CES2CES1TDP1MEN1KMT2A | |
| SCHEMBL6475119 | 0.79 | CNR1 (0.36) | CES2CES1MAPTLMNAUSP2 | |
| SCHEMBL6471957 | 0.76 | CES2 (0.47) | CES2CES1TDP1HDAC1MAPT | |
| SCHEMBL6471676 | 0.76 | CES2 (0.47) | CES2CES1TDP1HDAC1MAPT | |
| SCHEMBL6472144 | 0.74 | CES2 (0.46) | CES2CES1HDAC1MAPTLMNA | |
| SCHEMBL6527030 | 0.72 | CNR1 (0.37) | CES2CES1KMT2AMAPTLMNA | |
| SCHEMBL6528803 | 0.72 | MEN1 (0.41) | CES1TDP1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005109041-A1 | COMPOSITIONS FOR USE IN THE MANUFACTURE OF LENSES | MEDICAL POLYMERS LIMITED (GB) | 2005-11-17 | — | — | WO | disclosed |