Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.46 |
| ▸ | CES1 | P23141 | 5/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6471957 | 0.98 | CES2 (0.47) | CES2CES1TPMTCA1CA2 | |
| SCHEMBL6471676 | 0.98 | CES2 (0.47) | CES2CES1TPMTCA1CA2 | |
| SCHEMBL6471828 | 0.97 | CES2 (0.44) | CES2CES1TPMTCA1CA2 | |
| SCHEMBL6472518 | 0.76 | CES2 (0.40) | CES2CES1TPMTCA1CA2 | |
| SCHEMBL6472434 | 0.75 | CES2 (0.41) | CES2CES1USP2ALDH1A1LMNA | |
| SCHEMBL6472064 | 0.74 | CES2 (0.42) | CES2CES1USP2ALDH1A1LMNA | |
| SCHEMBL6472601 | 0.74 | CES2 (0.42) | CES2CES1USP2ALDH1A1LMNA | |
| SCHEMBL6474442 | 0.72 | CES2 (0.38) | CES2CES1USP2ALDH1A1LMNA | |
| SCHEMBL6476011 | 0.71 | TPMT (0.41) | CES1TPMTCA1CA2USP2 | |
| SCHEMBL4181175 | 0.70 | TPMT (0.64) | CES2CES1TPMTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005109041-A1 | COMPOSITIONS FOR USE IN THE MANUFACTURE OF LENSES | MEDICAL POLYMERS LIMITED (GB) | 2005-11-17 | — | — | WO | claimed |
| WO-2005109041-A1 | COMPOSITIONS FOR USE IN THE MANUFACTURE OF LENSES | MEDICAL POLYMERS LIMITED (GB) | 2005-11-17 | — | — | WO | disclosed |