SCHEMBL6472210

SCHEMBL6472210

COC(=O)c1ccccc1CCCCCOC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
LMNA P02545 3/20 0.56
TSHR P16473 5/20 0.48
DHODH Q02127 1/20 0.47
SCN1A P35498 2/20 0.47
SCN2A Q99250 2/20 0.47
SCN3A Q9NY46 2/20 0.47
SLC16A3 O15427 4/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TP53 P04637 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPK1 P28482 1/20 0.45
HIF1A Q16665 1/20 0.45
TDP1 Q9NUW8 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KDM4E B2RXH2 1/20 0.43
POLB P06746 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6436474 1.00 ALDH1A1 (0.56) ALDH1A1LMNATSHRDHODHSCN1A
SCHEMBL7643424 1.00 ALDH1A1 (0.56) ALDH1A1LMNATSHRDHODHSCN1A
SCHEMBL7200256 1.00 ALDH1A1 (0.56) ALDH1A1LMNATSHRDHODHSCN1A
SCHEMBL7643006 1.00 ALDH1A1 (0.56) ALDH1A1LMNATSHRDHODHSCN1A
SCHEMBL7639709 0.99 LMNA (0.57) ALDH1A1LMNATSHRDHODHSCN1A
SCHEMBL7639717 0.88 LMNA (0.59) ALDH1A1LMNATSHRDHODHSCN1A
SCHEMBL6467395 0.87 TSHR (0.54) ALDH1A1LMNATSHRSCN1ASCN2A
SCHEMBL7644390 0.87 TSHR (0.54) ALDH1A1LMNATSHRSCN1ASCN2A
SCHEMBL7036472 0.87 TSHR (0.54) ALDH1A1LMNATSHRSCN1ASCN2A
SCHEMBL6436959 0.82 LMNA (0.63) ALDH1A1LMNATSHRDHODHSLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1191064-B1 AROMATIC POLYCARBONATE COMPOSITION TEIJIN LTD (JP) 2005-12-07 EP disclosed
US-20030195329-A1 Aromatic polycarbonate, composition thereof , and use TEIJIN LIMITED (JP) 2003-10-16 US disclosed
US-6608165-B2 Melt polycondensing a dihydroxy compound and a carbonic acid diester in the presence of an ester exchange catalyst TEIJIN LIMITED (JP) 2003-08-19 US disclosed
US-20030060593-A1 Aromatic polycarbonate and process for their production TEIJIN LIMITED (JP) 2003-03-27 US disclosed
EP-1275694-A1 AROMATIC POLYCARBONATE COMPOSITION, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2003-01-15 EP disclosed
US-6448365-B1 Aromatic polycarbonate composition TEIJIN LIMITED (JP) 2002-09-10 US disclosed
US-20020103328-A1 Aromatic polycarbonate composition, production process therefor and molded product thereof TEIJIN LIMITED 2002-08-01 US disclosed
EP-1191064-A1 AROMATIC POLYCARBONATE COMPOSITION TEIJIN LIMITED (JP) 2002-03-27 EP disclosed