SCHEMBL647284

SCHEMBL647284

Cc1cc(C)c(S(=O)(=O)O)c(C)c1.NS

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
MMP1 P03956 1/20 0.52
MMP2 P08253 1/20 0.52
MMP9 P14780 1/20 0.52
MMP8 P22894 1/20 0.52
MMP13 P45452 1/20 0.52
F2 P00734 3/20 0.52
PRSS1 P07477 3/20 0.52
PRSS2 P07478 3/20 0.52
PRSS3 P35030 3/20 0.52
RAPGEF4 Q8WZA2 6/20 0.46
GAA P10253 3/20 0.42
POLB P06746 1/20 0.42
TSHR P16473 1/20 0.42
GFER P55789 1/20 0.42
MAPT P10636 3/20 0.41
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroxyamine SCHEMBL259333 0.93 CA1 (0.54) CA1CA2MMP1MMP2MMP9
SCHEMBL23788 0.93 CA1 (0.58) CA1CA2MMP1MMP2MMP9
SCHEMBL7930818 0.93 CA1 (0.58) CA1CA2MMP1MMP2MMP9
SCHEMBL10846507 0.93 CA1 (0.58) CA1CA2MMP1MMP2MMP9
Ammonia Solution, Strong SCHEMBL5999943 0.93 CA1 (0.58) CA1CA2MMP1MMP2MMP9
SCHEMBL2549047 0.91 CA1 (0.56) CA1CA2MMP1MMP2MMP9
Water SCHEMBL458685 0.91 CA1 (0.56) CA1CA2MMP1MMP2MMP9
SCHEMBL28656334 0.91 CA1 (0.56) CA1CA2MMP1MMP2MMP9
SCHEMBL9243736 0.91 CA1 (0.56) CA1CA2MMP1MMP2MMP9
SCHEMBL28505545 0.91 CA1 (0.56) CA1CA2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8143292-B2 N-Thio-anthranilamid compounds and their use as pesticides BASF SE (DE) 2012-03-27 US disclosed
US-8119568-B2 3-amino-1,2-benzisothiazole compounds for combating animal pest II BASF SE (DE) 2012-02-21 US disclosed
EP-1904475-B1 N-THIO-ANTHRANILAMID COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2011-08-17 EP disclosed
US-20100009848-A1 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II BASF SE (DE) 2010-01-14 US disclosed
EP-2064196-A2 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II BASF Aktiengesellschaft (DE) 2009-06-03 EP disclosed
WO-2008090048-A2 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II BASF SE (DE) 2008-07-31 WO disclosed
EP-1904475-A1 N-THIO-ANTHRANILAMID COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2008-04-02 EP disclosed
WO-2007006670-A1 N-THIO-ANTHRANILAMID COMPOUNDS AND THEIR USE AS PESTICIDES BASF AKTIENGESELLSCHAFT (DE) 2007-01-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100009848-A1 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II BPNT1, BCAT1, TGFBR1 CA1 995/4885CA2 838/4885MMP1 793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.